The setup took a matter of minutes (if you can read). Set your XBOX to use 5.1, install your favorite game and be blown away. I noticed you could turn the bass up and turn the volume all the way up, which is NOT a good idea. From what it sounds like, you can easily muck up your headset if you have a lot of bass filled games (shooters). It will also take a little time to tweak to get the right balance of voice chat + game.
All in all, these are worth the $130 investment. The movies I stream from Netflix are amazing, the music I get from Last.fm blew me away. These are one of the best headsets you can get for your XBOX 360.